Agaricus bisporus cultivated mushroom

2010 HUMAN Trials “suggest that the mushrooms and mushroom extracts tested are safe and generally well tolerated. Agaritine in cultivated Agaricus bisporus has been reported in some animal model studies to be associated with potential carcinogenic effects, although this has been challenged by others and contradicted by other studies in the same animal models. A very recent study has demonstrated that agaritine purified from Agaricus blazei has direct antitumor activity against leukemic tumor cells in vitro which is in contrast to the carcinogenic activity previously ascribed to this compound.

These data provide support for the conclusion of a recently published scientific critique of studies on agaritine which concluded that there is no scientifically substantiated data linking consumption of mushrooms to carcinogenicity in either animal models or humans.
https://happyherbivore.com/2017/05/mushroom-substitute-safe-eat-raw...

Preliminary evidence suggests that mushrooms may support healthy immune and inflammatory responses through interaction with the gut microbiota, enhancing the development of adaptive immunity, and improved immune cell functionality. In addition to imparting direct nutritional and health benefits, analysis of U.S. food intake survey data reveals that mushrooms are associated with higher dietary quality. Also, early sensory research suggests that mushrooms blended with meats and lower sodium dishes are well-liked and may help to reduce intakes of red meat and salt without compromising taste. As research progresses on the specific health effects of mushrooms, there is a need for effective communication efforts to leverage mushrooms to improve overall dietary quality. https://www.researchgate.net/publication/262193185_Mushrooms_and_He...

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