Shaggy Ink Cap Coprinuscomatus

[Mystic Wolf]

Shaggy Ink Cap Coprinuscomatus
The common inky cap mushroom is bell-shaped and has a striated surface on its cap. The cap is light grey or buff in color and has a ragged or pleated edge. As in the shaggy mane, the gills are white at first and then to turn to grey and finally to black. Also, as in the shaggy mane, the cap doesn't open up into an umbrella shape until autodigestion begins.
The shaggy ink cap mushroom, Coprinuscomatus belonging to Agaricomycete was evaluated for its anti-cancer potential. The effect of ethyl acetate extract was comparable to the effect of curcumin, a known NF-κB pathway inhibitor. The results promise that the mushroom extract can be an effective therapy for malignant estrogen-independent breast cancer (Asatiani et al. 2011). Zaidman et al. (2008) studied the selective inhibition of prostate cancer LNCaP cells by ethanol and ethyl acetate extracts of this mushroom. It was observed that this extract inhibits dihydrotestosterone-induced LNCaP cell viability and causes a G1 phase arrest. These findings suggested the therapeutic mechanism of the extract as an androgen receptor or non-androgen receptor-mediated.
https://healing-mushrooms.net/Coprinus-comatus
In other studies, the hypoglycemic activity of fermented mushroom of Coprinus comatus rich in vanadium was investigated. Vanadium salts have insulin-mimetic activity, and vanadium compounds are being studied as potentially orally active replacements for insulin. Vanadium salts mimic most of the effects of insulin in vitro and also induce normoglycemia and improve glucose homeostasis in insulin-deficient and insulin-resistant diabetic rodents in vivo. One study showed that Coprinus comatus fermentation liquid and sodium vanadate inhibited ascension of blood glucose in mice (Han et al., 2003).